I was hammering through all of my purchased games on the Ouya in CM11 using the Ouya Anywhere apks.
DRM really isn't that big of a concern in CM11 so long as the Framework has full access over the OS. If for some reason the user denies framework access then DRM will begin to fail on things like Nightmare Tower etc.
Bombsquad USED to be the most brutal about DRM and probably still is. However with the injection of the Cortex the developer compensated removing the console exclusion restriction off of his DRM which now makes it possible to play BombSquad from the Ouya Discover on your CM11 box.
The biggest problem is actually the home button. And how many developers due to the design of the Ouya were highly encouraged to use said home button as a 'start' menu schema for all games. The good news is the home button still does work! The bad news is the Trebuchet launcher ALSO likes the home button and will minimize your app which can get really really annoying.
I have not figured out how to move or re-map the home key for trebuchet to allow games to flow/function naturally again with the Ouya Controller.
Some of the developers which were initially programming their game for PC release were smart and also mapped the non-existent 'start' button of an xbox 360 controller into their Ouya App such as Duck Game. This regains access to those games as anyone with a Xbox 360 controller, wired playstation controller, or another brand of controller Mogo or GameStick can continue to happily play their game underneath CM11.
About the Ouya Framework: I do get the occasional crash when launching a non-Ouya game such as from the Google Play store. Probably because whatever game I am launching is asking for a similar DRM registration which makes the Ouya Framework panic and crash. This is only an annoyance as you just hit ok to close and the Ouya Framework service restarts again.